Epinephrine is a potent agonist of A1R and B1R with stronger B2R activity than norepinephrine. Epinephrine is approximately 100-fold more potent as an inotrope than dobutamine or dopamine, and low … Continue reading KNOW YOUR VASOPRESSORS AND INOTROPES – EPINEPHRINE (Part 3)
Month: August 2021
KNOW YOUR VASOPRESSORS AND INOTROPES – Norepinephrine – (Part 2)
Norepinephrine is a potent A1R agonist and mild–moderate B1R agonist with minimal B2R activity. The hemodynamic effects of norepinephrine are dominated by A1Rmediated vasoconstriction and increased SVR, while B1R activation … Continue reading KNOW YOUR VASOPRESSORS AND INOTROPES – Norepinephrine – (Part 2)
YOUR CVP IS NOT A MEASURE OF FLUID STATUS. WHY? Ten Points to Ponder
1. The central venous pressure, which is what we measure with a fluid filled catheter placed usually through the SVC down to the atrial junction. This pressure that we’re using … Continue reading YOUR CVP IS NOT A MEASURE OF FLUID STATUS. WHY? Ten Points to Ponder
KNOW YOUR VASOPRESSORS AND INOTROPES – DOBUTAMINE (Part I)
Dobutamine augments myocardial contractility via strong B1R stimulation with mild to moderate B2R agonism and mild A1R agonism, producing a strong dose-dependent increase in SV and CO with moderate increases … Continue reading KNOW YOUR VASOPRESSORS AND INOTROPES – DOBUTAMINE (Part I)
KNOW YOUR VASOPRESSORS AND INOTROPES – Introduction
Introduction Vasopressors are classified as drugs that are designed to increase arterial pressure by peripheral vasoconstriction. There are two types of vasopressors: pure vasoconstrictors and catecholamines. Pure vasoconstrictors only affect … Continue reading KNOW YOUR VASOPRESSORS AND INOTROPES – Introduction
‘Surgical Apgar’ Score Can Predict Postop Complications
In 1953, Virginia Apgar introduced a 10-point scoring system for evaluation of the condition of newborns, which revolutionized obstetric care. Similar to obstetrics in 1953, surgery today is without a … Continue reading ‘Surgical Apgar’ Score Can Predict Postop Complications